Speakers - 2026

Title: Infectious diseases with neurological involvement

Abstract

Background: Infectious diseases involving the central and peripheral nervous system represent a major challenge in clinical practice. Pathogens may affect the nervous system through direct invasion, immunemediated mechanisms, or secondary systemic inflammation. Conditions such as encephalitis, meningitis, and post-infectious neurological syndromes may lead to significant morbidity and long-term neurological impairment if not promptly diagnosed and treated.

Aim and Objectives: 

• To explore molecular and immunological mechanisms of neurological damage
• To discuss central and peripheral inflammatory responses
• To present selected clinical cases with neurological involvement
• To highlight diagnostic and therapeutic challenges in clinical practice 

Clinical Cases:

Case 1

• 45-year old-male
• Viral encephalitis
• MRI:tempo ral lobe inflammati on
• Outcome: Clinical recovery

Case 2 – Bacterial Meningitis

• 30-year-old female
• CSF findings: Elevated white blood cells, positive culture
• Outcome:
• Significant improvement

Diagnostic & Therapeutic Challenges:

• Difficulties in early pathogen identificationInterpret ation of neuroimaging findings
• Limited availability and specificity of biomarkers
• Need for individualized treatment strategies
• Prevention of longterm neurological sequelae

Treatment Strategies:

• Viral infections: Antiviral therapy
• Bacterial infections: Targeted antibiotic treatment
• Parasitic infections: Antiparasitic drugs
• Immunomodulation: Immune-based therapies
• Rehabilitation: Neurological support and long-term followup

Conclusions:
An integrative, evidencebased approach linking systemic infections to neurological manifestations is essential for optimal patient outcomes. Early diagnosis, multidisciplinary management, and personalized therapeutic strategies significantly improve prognosis and reduce long-term neurological complications.